Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | DBH | P09172 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13073814 | 0.72 | ADRA2C (0.48) | LMNAHTTSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL16378234 | 0.70 | MAOA (0.47) | KDM4ELMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15894142 | 0.69 | MAOA (0.46) | KDM4ELMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24508364 | 0.67 | KDM4E (0.73) | CYP2A13SIGMAR1KDM4ETDP1SMN1; SMN2 | |
| SCHEMBL593572 | 0.67 | CYP2A13 (0.66) | CYP2A13SIGMAR1KDM4ETDP1POLB | |
| SCHEMBL16378268 | 0.66 | ALDH1A1 (0.42) | LMNANPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL30596611 | 0.66 | KDM4E (0.71) | CYP2A13SIGMAR1KDM4ETDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8948250 | 0.66 | CYP2A13 (0.64) | CYP2A13SIGMAR1KDM4ETDP1LMNA | |
| SCHEMBL10842952 | 0.65 | SIGMAR1 (0.45) | CYP2A13SIGMAR1KDM4ETDP1DBH | |
| SCHEMBL9771445 | 0.65 | CYP2A13 (0.46) | CYP2A13SIGMAR1KDM4ETDP1DBH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050256167-A1 | Preparation and use of imidazole derivatives for treatment of obesity | BAYER PHARMACEUTICALS CORPORATION (US) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256167-A1 | Preparation and use of imidazole derivatives for treatment of obesity | GPR119, GIPR, PGC | CYP2A13 2364/4885SIGMAR1 2715/4885KDM4E 182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.