Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | NPC1 | O15118 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | STAT1 | P42224 | 1/20 | 0.62 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19625345 | 0.87 | SMN1; SMN2 (0.64) | PTGS1PTGS2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5698664 | 0.86 | PTGS2 (0.66) | PTGS1PTGS2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL17713571 | 0.81 | SMN1; SMN2 (0.57) | PTGS1PTGS2SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL13236931 | 0.80 | PTGS2 (0.65) | PTGS1PTGS2KMT2ACYP2C9CYP3A4 | |
| SCHEMBL23402744 | 0.78 | SMN1; SMN2 (0.69) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL6451935 | 0.78 | SMN1; SMN2 (0.69) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL3281219 | 0.78 | MAPK1 (0.56) | PTGS1SMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL1143708 | 0.77 | RAB9A (1.00) | PTGS1SMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL5698695 | 0.77 | PTGS2 (0.64) | PTGS1PTGS2CYP2C9EPHX2 | |
| SCHEMBL21849180 | 0.75 | GRN (0.56) | PTGS1PTGS2SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202367-B2 | Process for arylating or vinylating or alkynating a nucleophilic compound | RHODIA CHIMIE (FR) | 2007-04-10 | — | — | US | disclosed |
| US-20050234239-A1 | Method of forming a carbon-carbon or carbon-heteroatom linkage | SHASUN PHARMA SOLUTIONS, INC. | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234239-A1 | Method of forming a carbon-carbon or carbon-heteroatom linkage | AOC1, AOC3, NUDT1 | PTGS1 1096/4885PTGS2 965/4885SMN1; SMN2 3694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.