Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504861 | 0.92 | HPGD (0.39) | HPGDRAB9ANPC1TP53MAPT | |
| Trifluoroacetic Acid SCHEMBL6498995 | 0.89 | PPARG (0.39) | HPGDRAB9ANPC1TP53MAPT | |
| SCHEMBL6505057 | 0.89 | HPGD (0.48) | HPGDRAB9ANPC1P2RX7KMT2A | |
| SCHEMBL6497497 | 0.87 | S1PR3 (0.38) | HPGDRAB9AP2RX7S1PR3MEN1 | |
| Trifluoroacetic Acid SCHEMBL6504858 | 0.81 | HPGD (0.40) | HPGDRAB9AP2RX7ALDH1A1PPARG | |
| Trifluoroacetic Acid SCHEMBL6505054 | 0.77 | HPGD (0.49) | HPGDRAB9AP2RX7ALDH1A1PPARG | |
| Trifluoroacetic Acid SCHEMBL6497487 | 0.76 | S1PR3 (0.40) | S1PR3PPARGPPARA | |
| SCHEMBL6504395 | 0.76 | PPARA (0.37) | MAPTP2RX7PPARGPPARDPPARA | |
| SCHEMBL6505593 | 0.76 | ADORA2A (0.35) | HPGDRAB9ANPC1ALDH1A1PPARD | |
| SCHEMBL6494741 | 0.75 | PPARA (0.39) | MAPTPPARGPPARDPPARAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |