Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.41 |
| ▸ | ITGAV | P06756 | 6/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 6/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.41 |
| ▸ | APOB | P04114 | 2/20 | 0.41 |
| ▸ | MTTP | P55157 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6492604 | 0.92 | MTTP (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4ITGB3 | |
| SCHEMBL6789084 | 0.90 | SMO (0.48) | CHRNB2CHRNB4CHRNA3CHRNA4OPRL1 | |
| SCHEMBL6501001 | 0.89 | OPRL1 (0.43) | ITGB1ITGA5OPRL1APOBMTTP | |
| SCHEMBL6490835 | 0.87 | SMO (0.50) | APOBMTTPSMOEGLN1 | |
| SCHEMBL7133280 | 0.86 | SORT1 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA4ITGB3 | |
| SCHEMBL6502751 | 0.86 | CHRNB2 (0.44) | CHRNB2CHRNB4CHRNA3CHRNA4ITGB3 | |
| SCHEMBL6499727 | 0.85 | OPRL1 (0.43) | OPRL1APOBMTTPGCGRSMO | |
| SCHEMBL6491507 | 0.85 | MTTP (0.49) | CHRNB2CHRNB4CHRNA3CHRNA4OPRL1 | |
| SCHEMBL6490619 | 0.85 | ITGB3 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4ITGB3 | |
| SCHEMBL6497723 | 0.83 | APOB (0.46) | SORT1APOBMTTPSMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | CHRNB2 767/4885CHRNB4 2181/4885CHRNA3 1702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.