Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 2/20 | 0.35 |
| ▸ | PTPRB | P23467 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6500322 | 0.78 | SIRT1 (0.39) | SIRT1PI4KBHDAC3HDAC1HDAC2 | |
| SCHEMBL6492581 | 0.76 | SMN1; SMN2 (0.46) | SIRT1PI4KBAOC3NPC1ALDH1A1 | |
| SCHEMBL6683519 | 0.74 | L3MBTL1 (0.40) | HDAC1HDAC6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6495932 | 0.74 | AOC3 (0.54) | SIRT1PI4KBHDAC3HDAC1HDAC2 | |
| SCHEMBL16123390 | 0.73 | SIRT1 (0.52) | SIRT1PI4KBHDAC3HDAC1HDAC2 | |
| SCHEMBL21228025 | 0.72 | SIRT1 (0.48) | SIRT1PI4KBHDAC3HDAC1HDAC2 | |
| SCHEMBL1030124 | 0.72 | PI4KB (0.50) | SIRT1PI4KBHDAC3HDAC1HDAC2 | |
| SCHEMBL2175797 | 0.72 | SMN1; SMN2 (0.50) | SIRT1PI4KBHDAC3HDAC1HDAC2 | |
| SCHEMBL27583385 | 0.72 | SIRT1 (0.44) | SIRT1PI4KBHDAC3HDAC1HDAC2 | |
| SCHEMBL6491199 | 0.72 | SIRT1 (0.44) | SIRT1PI4KBHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | SIRT1 804/4885PI4KB 1625/4885HDAC3 557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.