Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 3/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL820669 | 0.92 | ACHE (0.52) | HSD17B2HSD17B1ALDH1A1TSHRMTNR1A | |
| SCHEMBL29636366 | 0.92 | ACHE (0.52) | HSD17B2HSD17B1ALDH1A1TSHRMTNR1A | |
| Hydrochloric Acid SCHEMBL2861521 | 0.90 | HSD17B2 (0.50) | HSD17B2HSD17B1ALDH1A1TSHRMTNR1A | |
| Nitrogen SCHEMBL4600737 | 0.88 | HSD17B2 (0.49) | HSD17B2HSD17B1ALDH1A1TSHRMTNR1A | |
| SCHEMBL30053811 | 0.85 | SMN1; SMN2 (0.55) | HSD17B2HSD17B1ALDH1A1TSHRMTNR1A | |
| SCHEMBL20838956 | 0.85 | SMN1; SMN2 (0.55) | HSD17B2HSD17B1ALDH1A1TSHRMTNR1A | |
| 1,3-Dimethoxybenzene SCHEMBL2348353 | 0.81 | ACHE (0.58) | ALDH1A1TSHRACHECES2CES1 | |
| SCHEMBL30054343 | 0.79 | MTNR1A (0.61) | HSD17B2HSD17B1ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL1134082 | 0.79 | MTNR1A (0.61) | HSD17B2HSD17B1ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL7850178 | 0.79 | CALM1 (0.46) | HSD17B2HSD17B1ALDH1A1TSHRMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855843-B2 | Inhibitors of α4 mediated cell adhesion | TANABE SEIYAKU CO., LTD. (JP) | 2005-02-15 | — | — | US | disclosed |
| US-20030191118-A1 | Inhibitors of alpha4 mediated cell adhesion | TANABE SEIYAKU CO., LTD. | 2003-10-09 | — | — | US | disclosed |
| US-6521666-B1 | Inhibitors of α4 mediated cell adhesion | TANABE SEIYAKU CO., LTD. (JP) | 2003-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191118-A1 | Inhibitors of alpha4 mediated cell adhesion | ITGB4, ITGA4, VCAM1 | HSD17B2 2653/4885HSD17B1 1936/4885ALDH1A1 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.