Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501868 | 0.95 | ALDH1A1 (0.49) | PKMALDH1A1LMNARXFP1L3MBTL1 | |
| SCHEMBL6504150 | 0.90 | ALDH1A1 (0.50) | PKMALDH1A1GAALMNARXFP1 | |
| SCHEMBL6502049 | 0.82 | HSD11B1 (0.41) | PKMALDH1A1GAALMNAKDM1A | |
| SCHEMBL6507303 | 0.69 | JAK2 (0.40) | PKMALDH1A1GAALMNAJAK2 | |
| SCHEMBL23043650 | 0.65 | MCOLN3 (0.60) | PKMALDH1A1GAALMNAL3MBTL1 | |
| SCHEMBL29978716 | 0.65 | MCOLN3 (0.60) | PKMALDH1A1GAALMNAL3MBTL1 | |
| SCHEMBL25352069 | 0.65 | GAA (0.69) | PKMALDH1A1GAALMNAKDM1A | |
| SCHEMBL24309298 | 0.63 | LMNA (0.56) | PKMALDH1A1GAALMNAL3MBTL1 | |
| SCHEMBL532980 | 0.63 | JAK2 (0.48) | PKMALDH1A1GAALMNARXFP1 | |
| SCHEMBL12478325 | 0.62 | FFAR4 (0.49) | PKMALDH1A1GAARXFP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014591-A1 | 2-ACYLAMINO OR 2-SULFONYLAMINO-1, 3-THIAZOLES AS COUPLERS FOR THE OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2005-02-17 | — | — | WO | claimed |