Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | CCR4 | P51679 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | MYLK | Q15746 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 2/20 | 0.36 |
| ▸ | EDNRA | P25101 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502050 | 0.82 | PKM (0.47) | ALDH1A1HPGDGAALMNAPKM | |
| SCHEMBL6504150 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HPGDGAALMNAPKM | |
| SCHEMBL6501868 | 0.77 | ALDH1A1 (0.49) | ALDH1A1HPGDLMNASLC40A1PKM | |
| SCHEMBL6508478 | 0.73 | SLC40A1 (0.37) | ALDH1A1GAALMNASLC40A1KDM4E | |
| SCHEMBL2762614 | 0.66 | KDM1A (0.69) | HSD11B1HSD17B1HSD17B2KDM1A | |
| SCHEMBL6507034 | 0.65 | HPGD (0.40) | ALDH1A1HPGDGAALMNAMAPT | |
| SCHEMBL3935864 | 0.64 | HSD11B1 (0.53) | HSD11B1CCR4ALDH1A1GAALMNA | |
| SCHEMBL5398845 | 0.64 | HSD11B1 (0.47) | HSD11B1HSD17B1HSD17B2CCR4ALDH1A1 | |
| SCHEMBL3625075 | 0.64 | HSD11B1 (0.61) | HSD11B1HSD17B1HSD17B2CCR4ALDH1A1 | |
| SCHEMBL3926626 | 0.64 | HSD11B1 (0.53) | HSD11B1CCR4ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014591-A1 | 2-ACYLAMINO OR 2-SULFONYLAMINO-1, 3-THIAZOLES AS COUPLERS FOR THE OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2005-02-17 | — | — | WO | claimed |