Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502050 | 0.90 | PKM (0.47) | ALDH1A1HPGDLMNAGAAPKM | |
| SCHEMBL6501868 | 0.83 | ALDH1A1 (0.49) | ALDH1A1HPGDLMNAPKMKDM4E | |
| SCHEMBL6502049 | 0.81 | HSD11B1 (0.41) | ALDH1A1HPGDLMNAGAAPKM | |
| SCHEMBL6507034 | 0.78 | HPGD (0.40) | ALDH1A1HPGDLMNAGAARXFP1 | |
| SCHEMBL24309298 | 0.70 | LMNA (0.56) | ALDH1A1HPGDLMNAGAAPKM | |
| SCHEMBL6502799 | 0.69 | LMNA (0.46) | ALDH1A1LMNAPKMKDM4ETP53 | |
| SCHEMBL25351654 | 0.67 | KMT2A (0.58) | ALDH1A1HPGDLMNAGAAKDM4E | |
| SCHEMBL617744 | 0.66 | ALDH1A1 (0.72) | ALDH1A1HPGDLMNAGAAPKM | |
| SCHEMBL25352069 | 0.66 | GAA (0.69) | ALDH1A1LMNAGAAPKMKDM4E | |
| SCHEMBL25352951 | 0.66 | KMT2A (0.65) | ALDH1A1LMNAGAAKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014591-A1 | 2-ACYLAMINO OR 2-SULFONYLAMINO-1, 3-THIAZOLES AS COUPLERS FOR THE OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2005-02-17 | — | — | WO | disclosed |