Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502050 | 0.95 | PKM (0.47) | ALDH1A1RXFP1L3MBTL1KDM1AMAOA | |
| SCHEMBL6504150 | 0.83 | ALDH1A1 (0.50) | ALDH1A1RXFP1L3MBTL1KDM1AHPGD | |
| SCHEMBL6507034 | 0.77 | HPGD (0.40) | ALDH1A1RXFP1L3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL6502049 | 0.77 | HSD11B1 (0.41) | ALDH1A1KDM1AHPGDKDM4EMAPT | |
| SCHEMBL23043650 | 0.69 | MCOLN3 (0.60) | ALDH1A1L3MBTL1JAK2KDM4ECYP3A4 | |
| SCHEMBL29978716 | 0.69 | MCOLN3 (0.60) | ALDH1A1L3MBTL1JAK2KDM4ECYP3A4 | |
| SCHEMBL532980 | 0.67 | JAK2 (0.48) | ALDH1A1RXFP1L3MBTL1JAK2HPGD | |
| SCHEMBL6502799 | 0.66 | LMNA (0.46) | ALDH1A1KDM4ESMN1; SMN2CYP3A4MAPT | |
| SCHEMBL11891721 | 0.64 | AKT1 (0.52) | ALDH1A1RXFP1L3MBTL1KDM1AMAOA | |
| SCHEMBL13539340 | 0.64 | ALDH1A1 (0.64) | ALDH1A1RXFP1L3MBTL1KDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014591-A1 | 2-ACYLAMINO OR 2-SULFONYLAMINO-1, 3-THIAZOLES AS COUPLERS FOR THE OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2005-02-17 | — | — | WO | disclosed |