Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3911268 | 0.86 | IDO1 (0.50) | CYP19A1IDO1TDO2CA1CA2 | |
| SCHEMBL5320250 | 0.82 | GAA (0.32) | CYP19A1CYP11B1CYP11B2NFE2L2 | |
| SCHEMBL7463502 | 0.81 | MAOB (0.42) | IDO1TDO2CA1CA2TSHR | |
| SCHEMBL6501428 | 0.80 | GAA (0.41) | CYP1A2CYP2D6TSHRMAPTKDM4E | |
| SCHEMBL5317299 | 0.77 | MAPKAPK2 (0.40) | CYP19A1CYP11B1CYP11B2SMN1; SMN2TSHR | |
| SCHEMBL3398965 | 0.77 | CYP19A1 (0.39) | CYP19A1NFE2L2IDO1TDO2TSHR | |
| SCHEMBL6508159 | 0.76 | ALDH1A1 (0.47) | CYP1A1CYP1A2CYP2D6CYP1B1SMN1; SMN2 | |
| SCHEMBL28475047 | 0.76 | IDO1 (0.44) | CYP19A1NFE2L2SMN1; SMN2IDO1TDO2 | |
| SCHEMBL1515763 | 0.75 | SLC6A3 (0.58) | CYP2D6POLBMAPTKDM4EHSD17B10 | |
| SCHEMBL23882694 | 0.75 | ACHE (0.49) | CYP19A1CYP11B1CYP11B2CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TNF, TRAF6, MMP8 | CYP19A1 2827/4885CYP11B1 2166/4885CYP11B2 2363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.