Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 5/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28743051 | 0.80 | GLS (0.41) | L3MBTL1LMNAKDM4E | |
| SCHEMBL8052157 | 0.73 | P2RX7 (0.47) | FAAHCYP2C19 | |
| SCHEMBL13091290 | 0.73 | TSHR (0.41) | RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL13104120 | 0.73 | ALDH1A1 (0.39) | SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL2298967 | 0.72 | NPC1 (0.41) | RAB9ASMN1; SMN2NPC1HPGDL3MBTL1 | |
| SCHEMBL30931653 | 0.72 | FAAH (0.41) | RAB9ASMN1; SMN2NPC1HPGDL3MBTL1 | |
| SCHEMBL2732148 | 0.71 | FAAH (0.40) | RAB9ASMN1; SMN2NPC1HPGDL3MBTL1 | |
| SCHEMBL6494414 | 0.70 | FFAR1 (0.48) | HPGDFAAHALDH1A1CYP1A2 | |
| SCHEMBL13387445 | 0.69 | FAAH (0.58) | RAB9ASMN1; SMN2NPC1LMNAFAAH | |
| SCHEMBL6499247 | 0.69 | MAPK1 (0.35) | MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |