Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28226288 | 0.82 | CYP1A2 (0.37) | GAANPC1RAB9AMAPK1MAPT | |
| SCHEMBL20504181 | 0.80 | NPSR1 (0.43) | HCAR2MAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL22774382 | 0.80 | L3MBTL1 (0.40) | HCAR2GAANPC1RAB9AMAPK1 | |
| SCHEMBL14773411 | 0.80 | ALDH1A1 (0.37) | HCAR2GAANPC1RAB9AMAPK1 | |
| SCHEMBL4852589 | 0.79 | NPSR1 (0.47) | GAANPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL6505364 | 0.79 | GAA (0.55) | GAANPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL7938433 | 0.78 | NPC1 (0.34) | HCAR2GAANPC1RAB9AMAPK1 | |
| SCHEMBL2474416 | 0.78 | GABRP (0.36) | HCAR2GAANPC1RAB9AMAPK1 | |
| SCHEMBL2477424 | 0.74 | RAB9A (0.33) | HCAR2GAANPC1RAB9AMAPK1 | |
| SCHEMBL3358641 | 0.74 | RAB9A (0.33) | HCAR2GAANPC1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |