Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | HTT | P42858 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | NSD2 | O96028 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 3/20 | 0.40 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6500883 | 0.86 | ALDH1A1 (0.48) | ALDH1A1HTTLMNAL3MBTL1NOD2 | |
| SCHEMBL6505425 | 0.80 | HSP90AA1 (0.61) | ALDH1A1HTTLMNAL3MBTL1HSP90AA1 | |
| SCHEMBL6508853 | 0.77 | ALDH1A1 (0.41) | ALDH1A1HTTLMNAL3MBTL1NOD2 | |
| SCHEMBL6509320 | 0.76 | TDP2 (0.49) | ALDH1A1HTTLMNAL3MBTL1NOD2 | |
| SCHEMBL31171425 | 0.72 | MEN1 (0.55) | ALDH1A1HTTLMNAL3MBTL1RAB9A | |
| SCHEMBL6240247 | 0.69 | MAOA (0.49) | ALDH1A1HTTLMNAL3MBTL1NOD2 | |
| SCHEMBL10465216 | 0.69 | POLB (0.66) | ALDH1A1HTTLMNAHSP90AA1RAB9A | |
| SCHEMBL29967684 | 0.68 | HKDC1 (0.51) | ALDH1A1HTTLMNAL3MBTL1RAB9A | |
| SCHEMBL6039993 | 0.67 | LMNA (0.53) | ALDH1A1HTTLMNAHSP90AA1GAA | |
| SCHEMBL4819698 | 0.66 | CYP1A2 (0.58) | ALDH1A1HTTLMNARAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050032794-A1 | Diamine derivatives of quinone and uses thereof | CLINICAL DATA, INC. | 2005-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032794-A1 | Diamine derivatives of quinone and uses thereof | NQO1, DPYD, NQO2 | ALDH1A1 128/4885HTT 3519/4885LMNA 3778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.