Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6499395 | 0.94 | BCHE (0.56) | BCHEL3MBTL1FFAR1EPHX2FFAR4 | |
| SCHEMBL6503729 | 0.88 | EPHX2 (0.58) | BCHEEPHX2TSHRHSD17B10KDM4E | |
| SCHEMBL6508701 | 0.86 | KDM4E (0.50) | BCHETSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL6499688 | 0.86 | CYP1A2 (0.56) | BCHEFFAR1TSHRHSD17B10KDM4E | |
| SCHEMBL6498720 | 0.84 | BCHE (0.59) | BCHEL3MBTL1TSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL6505559 | 0.83 | EPHX2 (0.56) | BCHEEPHX2TSHRHSD17B10ALDH1A1 | |
| SCHEMBL6500610 | 0.82 | GAA (0.59) | BCHEFFAR1FFAR4TSHRHSD17B10 | |
| SCHEMBL6507435 | 0.82 | RAB9A (0.49) | BCHETSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL6507792 | 0.80 | MTNR1A (0.51) | TSHRHSD17B10KDM4EGAAMEN1 | |
| SCHEMBL6506029 | 0.80 | LMNA (0.55) | BCHETSHRHSD17B10GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | CCR8, CCL11, CCR5 | BCHE 945/4885L3MBTL1 4677/4885FFAR1 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.