Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.61 |
| ▸ | CNR2 | P34972 | 2/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KLK7 | P49862 | 3/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1716394 | 0.89 | ACP3 (0.61) | ACP3CNR2CNR1ALDH1A1NPSR1 | |
| SCHEMBL6755554 | 0.87 | ACP3 (0.59) | ACP3CNR2CNR1ALDH1A1NPSR1 | |
| SCHEMBL28833357 | 0.85 | KLK7 (0.62) | ACP3CNR2CNR1ALDH1A1NPSR1 | |
| SCHEMBL7596731 | 0.85 | ACP3 (0.57) | ACP3CNR2CNR1ALDH1A1NPSR1 | |
| SCHEMBL4493891 | 0.85 | ACP3 (0.57) | ACP3CNR2CNR1ALDH1A1NPSR1 | |
| SCHEMBL2922278 | 0.84 | L3MBTL1 (0.69) | ACP3CNR2CNR1ALDH1A1NPSR1 | |
| Diphenylacetic Acid SCHEMBL8037692 | 0.82 | ACP3 (0.54) | ACP3CNR2CNR1ALDH1A1NPSR1 | |
| SCHEMBL28785765 | 0.82 | HDAC4 (0.70) | ACP3CNR2CNR1ALDH1A1NPSR1 | |
| SCHEMBL7044804 | 0.82 | LDHA (0.55) | ACP3CNR2CNR1ALDH1A1NPSR1 | |
| SCHEMBL7560417 | 0.81 | L3MBTL1 (0.66) | ACP3CNR2CNR1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6858739-B2 | Indole and benzimidazole 15-lipoxygenase inhibitors | WARNER-LAMBERT COMPANY (US) | 2005-02-22 | — | — | US | disclosed |
| US-20040038943-A1 | Indole and benzimidazole 15-lipoxygenase inhibitors | CONNOR DAVID THOMAS (US) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038943-A1 | Indole and benzimidazole 15-lipoxygenase inhibitors | ALOX15, ALOX5, ALOX12 | ACP3 4777/4885CNR2 173/4885CNR1 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.