Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505903 | 0.91 | MMP12 (0.64) | MMP12 | |
| SCHEMBL6506346 | 0.84 | KMT2A (0.43) | MMP12TSHRKMT2AMEN1 | |
| SCHEMBL6501058 | 0.83 | OPRM1 (0.47) | — | |
| SCHEMBL2939724 | 0.83 | MMP12 (0.54) | MMP12TSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1532473 | 0.83 | MMP12 (0.54) | MMP12TSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6499912 | 0.83 | CYP4F2 (0.53) | SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7279889 | 0.81 | MMP12 (0.68) | MMP12TSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29257741 | 0.78 | MMP12 (0.52) | MMP12TSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7344016 | 0.78 | PPARG (0.55) | MMP12TSHRALDH1A1 | |
| SCHEMBL7344014 | 0.78 | PPARG (0.55) | MMP12TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1290819-C | 2-aminopropane-1,3-glycol compound, its use as medicine and its synthetic intermediate | MITSUBISHI PHARMACEUTICAL CO L (JP) | 2006-12-20 | — | — | CN | disclosed |
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |
| CN-1480450-A | 2-aminopropane-1,3-glycol compound, its use as medicine and its synthetic intermediate | ������ҩ��ʽ���� | 2004-03-10 | — | — | CN | disclosed |
| CN-1137086-C | 2-aminopropane-1, 3-diol compound, use thereof as medicine and synthetic intermediate thereof | ������ҩ��ʽ���� | 2004-02-04 | — | — | CN | disclosed |
| CN-1259117-A | 2-aminopropane-1, 3-diol compound, use thereof as medicine and synthetic intermediate thereof | YOSHITOMI PHARMACEUTICAL (JP) | 2000-07-05 | — | — | CN | disclosed |