Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 6/20 | 0.64 |
| ▸ | MMP13 | P45452 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505017 | 0.91 | MMP12 (0.51) | MMP12 | |
| SCHEMBL6506346 | 0.82 | KMT2A (0.43) | MMP12FFAR1ACACB | |
| SCHEMBL6505454 | 0.80 | ACACB (0.49) | MMP12FFAR1ACACBFDFT1 | |
| SCHEMBL14088203 | 0.79 | MMP12 (0.54) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL5694346 | 0.78 | MMP12 (1.00) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL14088202 | 0.78 | MMP12 (0.55) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL8716757 | 0.76 | MMP12 (0.56) | MMP12FFAR1MMEACACBPDCD1 | |
| SCHEMBL8161050 | 0.76 | MMP12 (0.53) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL6501058 | 0.75 | OPRM1 (0.47) | — | |
| SCHEMBL14088148 | 0.75 | MMP12 (0.70) | MMP12MMP13MMP2MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |