Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505017 | 0.84 | MMP12 (0.51) | KMT2AMMP12MEN1TSHR | |
| SCHEMBL6505903 | 0.82 | MMP12 (0.64) | MMP12ACACBFFAR1 | |
| SCHEMBL6501058 | 0.75 | OPRM1 (0.47) | CYP3A4 | |
| SCHEMBL10187974 | 0.74 | KMT2A (0.62) | KMT2AHSP90AA1ACACBPOLBCYP1A2 | |
| SCHEMBL6506348 | 0.73 | KMT2A (0.40) | KMT2AMMP12HSP90AA1POLBEPHX1 | |
| SCHEMBL1624417 | 0.70 | TAAR1 (0.47) | KMT2AHSP90AA1POLBEPHX1CTDSP1 | |
| SCHEMBL8874714 | 0.70 | KMT2A (0.38) | KMT2AMMP12HSP90AA1POLBEPHX1 | |
| SCHEMBL8874702 | 0.70 | KMT2A (0.38) | KMT2AMMP12HSP90AA1POLBEPHX1 | |
| SCHEMBL6768070 | 0.69 | TAAR1 (0.50) | KMT2AHSP90AA1POLBEPHX1CTDSP1 | |
| SCHEMBL4668894 | 0.69 | ALDH1A1 (0.45) | KMT2APOLBCTDSP1MAOBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |