Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509242 | 0.88 | MAOB (0.54) | MAOBPKMMAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL6504357 | 0.87 | MAOB (0.53) | MAOBPKMMAPTLMNAKMT2A | |
| SCHEMBL12385993 | 0.86 | PDE4B (0.41) | MAOBPDE4BPDE4DPKMLMNA | |
| SCHEMBL6503677 | 0.86 | PDE4B (0.41) | MAOBPDE4BPDE4DPKMLMNA | |
| SCHEMBL3903162 | 0.84 | MAOB (0.48) | MAOBPKMKMT2AHTR2AHTR2C | |
| SCHEMBL6500880 | 0.83 | LMNA (0.51) | PDE4BPDE4DPKMMAPTLMNA | |
| SCHEMBL6510748 | 0.79 | HTR6 (0.46) | MAOBPKMKMT2AHTR2AHTR2C | |
| SCHEMBL6502583 | 0.79 | LMNA (0.48) | PKMMAPTLMNAL3MBTL1TSHR | |
| SCHEMBL6504564 | 0.78 | HTR6 (0.54) | PDE4BMAPTLMNAL3MBTL1TSHR | |
| SCHEMBL3895372 | 0.78 | KMT2A (0.48) | MAOBPKMSMN1; SMN2KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014578-A1 | PHENYLSULFONYL COMPOUNDS AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-17 | — | — | WO | claimed |
| WO-2005014578-A1 | PHENYLSULFONYL COMPOUNDS AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-17 | — | — | WO | disclosed |