Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502583 | 0.91 | LMNA (0.48) | HTR6ALDH1A1HPGDDRD2HTR2A | |
| SCHEMBL6500880 | 0.91 | LMNA (0.51) | HTR6MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL6509242 | 0.90 | MAOB (0.54) | HTR6MEN1KMT2AHTR2AHTR2C | |
| SCHEMBL6504564 | 0.90 | HTR6 (0.54) | HTR6DRD2HTR2AHTR2CDRD3 | |
| Hydrochloric Acid SCHEMBL6504357 | 0.89 | MAOB (0.53) | HTR6MEN1KMT2AHTR2AHTR2C | |
| SCHEMBL6500166 | 0.87 | HTR1A (0.43) | HTR6MAPK1HSD17B10DRD2DRD3 | |
| SCHEMBL6507562 | 0.87 | MAPT (0.57) | HTR6ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6508601 | 0.87 | TNF (0.48) | ALDH1A1KMT2APOLB | |
| SCHEMBL6511504 | 0.87 | DRD2 (0.52) | MAPK1ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL6508620 | 0.87 | MAPT (0.49) | HTR6HSD17B10DRD2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014578-A1 | PHENYLSULFONYL COMPOUNDS AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-17 | — | — | WO | claimed |
| WO-2005014578-A1 | PHENYLSULFONYL COMPOUNDS AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-17 | — | — | WO | disclosed |