Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD5 | P21918 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507562 | 0.91 | MAPT (0.57) | LMNAPOLBHTR6ALDH1A1MAPT | |
| SCHEMBL6511504 | 0.91 | DRD2 (0.52) | LMNAPOLBALDH1A1MAPTDRD3 | |
| SCHEMBL6500880 | 0.91 | LMNA (0.51) | LMNAPOLBDRD1DRD5HTR6 | |
| SCHEMBL6510748 | 0.91 | HTR6 (0.46) | POLBHTR6ALDH1A1PKMHPGD | |
| SCHEMBL6501509 | 0.90 | HTR6 (0.46) | LMNAPOLBHTR6ALDH1A1MAPT | |
| SCHEMBL6509242 | 0.90 | MAOB (0.54) | LMNAHTR6PKMMAPTHTR2A | |
| SCHEMBL6504564 | 0.90 | HTR6 (0.54) | LMNADRD4HTR6MAPTDRD3 | |
| SCHEMBL6506073 | 0.89 | LMNA (0.44) | LMNAPOLBDRD1DRD4DRD5 | |
| SCHEMBL6500166 | 0.89 | HTR1A (0.43) | LMNADRD1DRD4DRD5HTR6 | |
| Hydrochloric Acid SCHEMBL6504357 | 0.89 | MAOB (0.53) | LMNAHTR6PKMMAPTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014578-A1 | PHENYLSULFONYL COMPOUNDS AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-17 | — | — | WO | claimed |
| WO-2005014578-A1 | PHENYLSULFONYL COMPOUNDS AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-02-17 | — | — | WO | disclosed |