Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505584 | 0.92 | DGAT1 (0.38) | FFAR2HPGDNPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6503012 | 0.91 | MAPT (0.39) | FFAR2ALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL7684255 | 0.90 | SHMT1 (0.40) | HPGDNPSR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6506148 | 0.89 | KMT2A (0.38) | FFAR2ALDH1A1SMN1; SMN2KCNH2RXFP1 | |
| SCHEMBL7676306 | 0.85 | MAPT (0.42) | HPGDNPSR1ALDH1A1MAPTGAA | |
| SCHEMBL6496054 | 0.83 | KDM4E (0.40) | HPGDNPSR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6498480 | 0.82 | CTSA (0.39) | ALDH1A1SMN1; SMN2MAPTGAATP53 | |
| SCHEMBL6496229 | 0.80 | SHMT1 (0.36) | HPGDALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL6495548 | 0.79 | TP53 (0.40) | HPGDNPSR1SMN1; SMN2MAPTGAA | |
| SCHEMBL6495786 | 0.77 | NPC1 (0.38) | NPSR1ALDH1A1SMN1; SMN2GAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |