Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6496229 | 0.91 | SHMT1 (0.36) | KMT2AHTTMEN1RXFP1ACACB | |
| SCHEMBL6496508 | 0.89 | FFAR2 (0.35) | KMT2AHTTMEN1RXFP1FFAR2 | |
| SCHEMBL6497551 | 0.88 | P2RX3 (0.37) | KMT2AHTTMEN1RXFP1ACACB | |
| SCHEMBL6505584 | 0.87 | DGAT1 (0.38) | KMT2AMEN1RXFP1FFAR2ACACB | |
| SCHEMBL6495943 | 0.86 | FFAR1 (0.39) | ACACBPPARAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL6503012 | 0.86 | MAPT (0.39) | KMT2AMEN1RXFP1FFAR2ACACB | |
| SCHEMBL7684255 | 0.79 | SHMT1 (0.40) | HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL6496054 | 0.78 | KDM4E (0.40) | KMT2AHTTMEN1ACACBALDH1A1 | |
| SCHEMBL6498480 | 0.78 | CTSA (0.39) | P2RX7ALDH1A1SMN1; SMN2 | |
| SCHEMBL6506146 | 0.75 | EPHX2 (0.37) | FFAR2PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |