SCHEMBL503349

SCHEMBL503349

N[C@@H](CSc1nccs1)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.42
FDPS P14324 1/20 0.42
PTGFR P43088 1/20 0.42
FBP1 P09467 4/20 0.41
PDK1 Q15118 1/20 0.41
GRIK1 P39086 1/20 0.41
GRIA1 P42261 1/20 0.41
GRIA2 P42262 1/20 0.41
GRIA3 P42263 1/20 0.41
GRIA4 P48058 1/20 0.41
GRIK2 Q13002 1/20 0.41
GRIK3 Q13003 1/20 0.41
GRIK4 Q16099 1/20 0.41
GRIK5 Q16478 1/20 0.41
KIF11 P52732 7/20 0.39
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
HSD17B3 P37058 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21240743 1.00 HTR7 (0.42) HTR7FDPSPTGFRFBP1PDK1
SCHEMBL11012213 0.74 HTR7 (0.49) HTR7FDPSPTGFRFBP1PDK1
SCHEMBL11522152 0.73 HTR7 (0.47) HTR7FDPSFBP1PDK1GAA
SCHEMBL503186 0.72 KIF11 (0.52) PTGFRKIF11RAB9A
SCHEMBL7350753 0.72 KIF11 (0.52) PTGFRKIF11RAB9A
SCHEMBL11446293 0.72 HTR7 (0.55) HTR7FDPSPTGFRFBP1PDK1
SCHEMBL5514921 0.71 FDPS (0.53) FDPSGRIK1GRIA1GRIA2GRIA3
SCHEMBL456949 0.71 FDPS (0.53) FDPSGRIK1GRIA1GRIA2GRIA3
SCHEMBL156953 0.71 FDPS (0.53) FDPSGRIK1GRIA1GRIA2GRIA3
Serine SCHEMBL359193 0.71 ALDH1A1 (0.44) GRIK1GRIA1GRIA2GRIA3GRIA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116120936-B Etching liquid medicine and preparation method and application thereof 上海天承化学有限公司 2024-06-25 CN claimed
CN-116120936-A Etching liquid medicine and preparation method and application thereof 上海天承化学有限公司 2023-05-16 CN claimed
US-11274126-B2 pH-sensitive cyclic peptides UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) 2022-03-15 US claimed
CN-105264064-B O-phosphoserine export proteins and methods of producing O-phosphoserine using the same CJ第一制糖株式会社 2020-08-18 CN claimed
EP-3348567-B1 NOVEL O-PHOSPHOSERINE EFFLUX PROTEIN VARIANT AND METHOD FOR PRODUCING O-PHOSPHOSERINE, CYSTEINE AND DERIVATIVE THEREOF USING SAME CJ CHEILJEDANG CORP (KR) 2020-08-05 EP claimed
EP-3181685-B1 O-PHOSPHOSERINE PRODUCING MICROORGANISM AND METHOD FOR PRODUCING O-PHOSPHOSERINE OR L-CYSTEINE USING SAME CJ CHEILJEDANG CORP (KR) 2019-08-14 EP claimed
EP-3432908-A1 pH-SENSITIVE PEPTIDES Rhode Island Council on Postsecondary Education (US) 2019-01-30 EP claimed
WO-2017165452-A1 pH-SENSITIVE PEPTIDES RHODE ISLAND COUNCIL ON POSTSECONDARY EDUCATION (US) 2017-09-28 WO claimed
US-12529082-B2 O-phosphoserine export protein variant and method for producing O-phosphoserine, cysteine, and derivatives thereof using the same CJ CHEILJEDANG CORPORATION (KR) 2026-01-20 US disclosed
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY (US) 2026-01-01 US disclosed
US-20250376493-A1 NOVEL YhhS VARIANT AND METHOD FOR PRODUCING O-PHOSPHOSERINE, CYSTEINE, AND DERIVATE OF CYSTEINE USING SAME CJ CHEILJEDANG CORPORATION (KR) 2025-12-11 US disclosed
US-12371461-B2 Nemo coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2025-07-29 US disclosed
EP-3303367-B1 STABILIZED MINIMAL COILED-COIL MIMETICS UNIV NEW YORK (US) 2025-06-18 EP disclosed
US-12290575-B2 Fluorescent compound comprising a fluorophore conjugated to a pH-triggered polypeptide UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) 2025-05-06 US disclosed
EP-1191106-B1 Process for the fermentative preparation of non-proteinogenic L-amino acids CONSORTIUM ELEKTROCHEM IND (DE) 2004-04-28 EP disclosed
US-6579705-B2 Generating preferential amino acid sequences; obtain adjusted amino acid, incubate with enzyme, recover amino acid CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 2003-06-17 US disclosed
US-20020177196-A1 Process for preparing non-proteinogenic L-amino acids CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH 2002-11-28 US disclosed
EP-1247869-A1 Process for the production of non-proteinogenic amino acids Consortium für elektrochemische Industrie GmbH (DE) 2002-10-09 EP disclosed
US-20020039767-A1 Process for producing non-proteinogenic L-amino acids by fermentation CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH 2002-04-04 US disclosed
EP-1191106-A1 Verfahren zur fermentativen Herstellung von nicht-proteinogenen L-Aminosäuren Consortium für elektrochemische Industrie GmbH (DE) 2002-03-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11274126-B2 pH-sensitive cyclic peptides VIP, PHLPP1, PHLPP2 HTR7 2572/4885FDPS 2920/4885PTGFR 1080/4885
US-12371461-B2 Nemo coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH HTR7 4286/4885FDPS 3526/4885PTGFR 2655/4885
US-20020039767-A1 Process for producing non-proteinogenic L-amino acids by fermentation CBS, BCAT2, BCAT1 HTR7 3900/4885FDPS 111/4885PTGFR 2456/4885
US-12290575-B2 Fluorescent compound comprising a fluorophore conjugated to a pH-triggered polypeptide NPPA, LNPEP, VIP HTR7 1706/4885FDPS 3248/4885PTGFR 879/4885
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME DDX21, PHAX, RBX1 HTR7 3548/4885FDPS 4648/4885PTGFR 3405/4885
US-12529082-B2 O-phosphoserine export protein variant and method for producing O-phosphoserine, cysteine, and derivatives thereof using the same PSPH, PHAX, MARS1 HTR7 4510/4885FDPS 113/4885PTGFR 4622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.