Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.49 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.49 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6513329 | 0.85 | MAPK1 (0.53) | RAB9AMAPK1CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL6508890 | 0.83 | LMNA (0.48) | RAB9AMAPK1CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL6510224 | 0.83 | RAB9A (0.50) | RAB9AMAPK1CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL6507568 | 0.79 | RAB9A (0.72) | RAB9AMAPK1MEN1KMT2ANPC1 | |
| SCHEMBL5923165 | 0.73 | MEN1 (0.46) | RAB9AMAPK1CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL10501633 | 0.71 | ADORA2A (0.56) | RAB9AMAPK1MEN1KMT2ANPC1 | |
| SCHEMBL10501630 | 0.71 | ADORA2A (0.56) | RAB9AMAPK1MEN1KMT2ANPC1 | |
| SCHEMBL6512568 | 0.71 | CRHBP (0.53) | RAB9AMAPK1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL14862522 | 0.70 | RAC1 (0.52) | RAB9AMAPK1MEN1KMT2ANPC1 | |
| SCHEMBL14861786 | 0.68 | SIGMAR1 (0.65) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095345-A2 | HETEROARYL GUANIDINES AS INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS, INC. (US) | 2005-10-13 | — | — | WO | claimed |