Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | SCN8A | Q9UQD0 | 5/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502797 | 0.84 | SLC40A1 (0.39) | SLC40A1SCN9AMAPTHSD17B10USP2 | |
| SCHEMBL6502799 | 0.72 | LMNA (0.46) | SCN9AMAPTHSD17B10USP2ESR2 | |
| SCHEMBL6504150 | 0.68 | ALDH1A1 (0.50) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL6501868 | 0.65 | ALDH1A1 (0.49) | SLC40A1MAPTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL6507034 | 0.63 | HPGD (0.40) | MAPTHSD17B10SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11973683 | 0.56 | SLC40A1 (1.00) | SLC40A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14683655 | 0.55 | ALDH1A1 (0.62) | SCN9AMAPTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL30925505 | 0.55 | SLC40A1 (0.77) | SLC40A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL27214250 | 0.55 | SLC40A1 (0.77) | SLC40A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL22567942 | 0.54 | USP2 (0.70) | SCN9AMAPTHSD17B10USP2ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014591-A1 | 2-ACYLAMINO OR 2-SULFONYLAMINO-1, 3-THIAZOLES AS COUPLERS FOR THE OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2005-02-17 | — | — | WO | disclosed |