Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502797 | 0.86 | SLC40A1 (0.39) | LMNASMN1; SMN2MAPTHSD17B10USP2 | |
| SCHEMBL6508478 | 0.72 | SLC40A1 (0.37) | LMNASMN1; SMN2MAPTHSD17B10USP2 | |
| SCHEMBL14683655 | 0.71 | ALDH1A1 (0.62) | LMNASMN1; SMN2MAPTALDH1A1KMT2A | |
| SCHEMBL6504150 | 0.69 | ALDH1A1 (0.50) | LMNASMN1; SMN2MAPTALDH1A1KMT2A | |
| SCHEMBL6501864 | 0.69 | USP2 (0.51) | MAPTHSD17B10USP2ESR2SCN9A | |
| SCHEMBL6507034 | 0.67 | HPGD (0.40) | LMNASMN1; SMN2MAPTHSD17B10ALDH1A1 | |
| SCHEMBL6501868 | 0.66 | ALDH1A1 (0.49) | LMNASMN1; SMN2MAPTALDH1A1KMT2A | |
| SCHEMBL2626467 | 0.64 | ALDH1A1 (0.59) | LMNASMN1; SMN2MAPTALDH1A1KMT2A | |
| SCHEMBL2626421 | 0.63 | KMT2A (0.60) | LMNASMN1; SMN2MAPTALDH1A1KMT2A | |
| SCHEMBL28780801 | 0.63 | LMNA (0.57) | LMNASMN1; SMN2MAPTHSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014591-A1 | 2-ACYLAMINO OR 2-SULFONYLAMINO-1, 3-THIAZOLES AS COUPLERS FOR THE OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2005-02-17 | — | — | WO | claimed |