Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | STAT6 | P42226 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515754 | 0.82 | SLC6A2 (0.57) | KDM4ETSHRSLC6A3ABCB11LMNA | |
| SCHEMBL7377129 | 0.81 | ATM (0.42) | KDM4ELMNACYP3A4CYP2C9NPC1 | |
| SCHEMBL6176982 | 0.80 | FFAR1 (0.44) | KDM4ESLC6A3LMNACYP3A4HIF1A | |
| SCHEMBL20681679 | 0.79 | RAB9A (0.45) | AHRKDM4ETSHRLMNANPC1 | |
| SCHEMBL1515694 | 0.79 | ACP3 (0.56) | LMNACYP3A4CYP2C9NPC1RAB9A | |
| SCHEMBL4775938 | 0.78 | ALDH1A1 (0.52) | KDM4ETSHRCYP3A4PKMRAB9A | |
| SCHEMBL7506748 | 0.78 | GRM5 (0.42) | KDM4ETSHRCYP3A4NPC1RAB9A | |
| SCHEMBL7097655 | 0.77 | NFE2L2 (0.44) | KDM4ETSHRLMNACYP3A4MAPT | |
| SCHEMBL23610031 | 0.76 | SLC10A1 (0.54) | AHRKDM4ETSHRSLC6A3ABCB11 | |
| SCHEMBL11722266 | 0.76 | AHR (0.54) | AHRKDM4ETSHRSLC6A3ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TNF, TRAF6, MMP8 | AHR 4671/4885KDM4E 4034/4885TSHR 3997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.