Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | RHOA | P61586 | 1/20 | 0.52 |
| ▸ | TXNRD1 | Q16881 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NEK2 | P51955 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5219253 | 0.85 | TXNRD1 (0.47) | TDP1POLBL3MBTL1TXNRD1MAPT | |
| Hydrochloric Acid SCHEMBL5220902 | 0.83 | TXNRD1 (0.49) | TDP1POLBTXNRD1MAPTALDH1A1 | |
| SCHEMBL2421463 | 0.82 | ALDH1A1 (0.64) | TDP1POLBTXNRD1MAPTALDH1A1 | |
| SCHEMBL5752857 | 0.82 | ALDH1A1 (0.64) | TDP1POLBTXNRD1MAPTALDH1A1 | |
| SCHEMBL5134790 | 0.82 | RHOA (0.46) | TDP1POLBL3MBTL1RHOATXNRD1 | |
| SCHEMBL1070995 | 0.81 | GPR119 (0.43) | TDP1POLBL3MBTL1RHOAMAPT | |
| SCHEMBL6509373 | 0.81 | TXNRD1 (0.47) | TDP1POLBTXNRD1MAPTALDH1A1 | |
| SCHEMBL6229685 | 0.80 | RHOA (0.44) | TDP1POLBL3MBTL1RHOAMAPT | |
| SCHEMBL1252463 | 0.80 | TRPV1 (0.54) | TXNRD1MAPTALDH1A1NPSR1 | |
| SCHEMBL30435070 | 0.80 | SIRT6 (0.54) | TDP1POLBTXNRD1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168827-B2 | Amide derivative | AJINOMOTO CO., INC. (JP) | 2012-05-01 | — | — | US | disclosed |
| US-20090258900-A1 | AMIDE DERIVATIVE | AJINOMOTO CO. INC (JP) | 2009-10-15 | — | — | US | disclosed |
| US-7572815-B2 | Amide derivative | AJINOMOTO CO., INC. (JP) | 2009-08-11 | — | — | US | disclosed |
| US-20060128755-A1 | Amide derivative | AJINOMOTO CO. INC (JP) | 2006-06-15 | — | — | US | disclosed |
| EP-1627869-A1 | AMIDE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2006-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128755-A1 | Amide derivative | NR0B1, NR0B2, NR1I3 | TDP1 4764/4885POLB 367/4885L3MBTL1 3641/4885 |
| US-20090258900-A1 | AMIDE DERIVATIVE | NR0B1, NR0B2, NR1I3 | TDP1 4806/4885POLB 408/4885L3MBTL1 3307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.