Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 6/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | CRHBP | P24387 | 2/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2689490 | 0.85 | TDP1 (0.52) | TXNRD1ALDH1A1MAPTMAPK1POLB | |
| SCHEMBL5752950 | 0.85 | TXNRD1 (0.48) | TXNRD1OPRK1ALDH1A1 | |
| SCHEMBL3281560 | 0.82 | OPRK1 (0.40) | TXNRD1OPRK1ALDH1A1CRHBPCRHR2 | |
| Hydrochloric Acid SCHEMBL5220902 | 0.80 | TXNRD1 (0.49) | TXNRD1ALDH1A1MAPTMAPK1POLB | |
| SCHEMBL19691739 | 0.80 | TXNRD1 (0.46) | TXNRD1ALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL19691737 | 0.80 | TXNRD1 (0.46) | TXNRD1ALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL5752857 | 0.79 | ALDH1A1 (0.64) | TXNRD1ALDH1A1MAPTMAPK1POLB | |
| SCHEMBL2421463 | 0.79 | ALDH1A1 (0.64) | TXNRD1ALDH1A1MAPTMAPK1POLB | |
| SCHEMBL6509373 | 0.78 | TXNRD1 (0.47) | TXNRD1ALDH1A1MAPTMAPK1POLB | |
| SCHEMBL30435070 | 0.77 | SIRT6 (0.54) | TXNRD1ALDH1A1MAPTMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664025-B1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2007-09-19 | — | — | EP | disclosed |