Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 3/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 8/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510623 | 0.85 | RAB9A (0.67) | CRHBPCRHR2RAB9AMEN1KMT2A | |
| SCHEMBL5923100 | 0.77 | GAA (0.44) | FAAH | |
| SCHEMBL6511099 | 0.76 | CRHBP (0.57) | CRHBPCRHR2RAB9AMEN1KMT2A | |
| SCHEMBL4983220 | 0.76 | ADRA2A (0.66) | FAAHSIGMAR1 | |
| SCHEMBL6508134 | 0.76 | CRHBP (0.51) | CRHBPCRHR2RAB9AMEN1KMT2A | |
| SCHEMBL9622519 | 0.75 | SMN1; SMN2 (0.42) | CRHBPCRHR2RAB9AKMT2AMAPK1 | |
| SCHEMBL6512924 | 0.73 | CRHBP (0.68) | CRHBPCRHR2RAB9AMEN1KMT2A | |
| SCHEMBL5923088 | 0.71 | MAPT (0.48) | MEN1KMT2ALMNAPOLBFAAH | |
| SCHEMBL27683655 | 0.70 | FAAH (0.58) | FAAH | |
| SCHEMBL3428651 | 0.70 | PTGES (0.58) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095345-A2 | HETEROARYL GUANIDINES AS INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS, INC. (US) | 2005-10-13 | — | — | WO | claimed |