Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 3/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508975 | 0.79 | MEN1 (0.53) | CRHBPCRHR2RAB9AMEN1KMT2A | |
| SCHEMBL6509463 | 0.76 | CRHBP (0.58) | CRHBPCRHR2RAB9AMEN1KMT2A | |
| SCHEMBL4983220 | 0.75 | ADRA2A (0.66) | FAAHADRA2A | |
| SCHEMBL5923126 | 0.75 | CHRNB2 (0.50) | RAB9AMEN1KMT2ALMNAPOLB | |
| SCHEMBL6512568 | 0.73 | CRHBP (0.53) | CRHBPCRHR2RAB9AMEN1KMT2A | |
| SCHEMBL6508134 | 0.71 | CRHBP (0.51) | CRHBPCRHR2RAB9AMEN1KMT2A | |
| SCHEMBL5923381 | 0.71 | MAPT (0.55) | KMT2ALMNAFAAHKDM4EMAPT | |
| SCHEMBL5923063 | 0.70 | MAPT (0.54) | KMT2AFAAHKDM4EMAPTHPGD | |
| SCHEMBL3428651 | 0.70 | PTGES (0.58) | FAAHHPGD | |
| SCHEMBL27683655 | 0.70 | FAAH (0.58) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095345-A2 | HETEROARYL GUANIDINES AS INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS, INC. (US) | 2005-10-13 | — | — | WO | claimed |