Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511127 | 0.94 | PKM (0.38) | PKMFOLH1MEN1KMT2AFFAR1 | |
| SCHEMBL6516556 | 0.92 | LTA4H (0.45) | KMT2AFFAR1SMN1; SMN2HSP90AA1HSP90AB1 | |
| SCHEMBL6512357 | 0.90 | TAS2R14 (0.43) | MEN1KMT2AHSP90AA1LMNAMEP1B | |
| SCHEMBL6510153 | 0.90 | PKM (0.47) | PKMFOLH1MEN1KMT2AFFAR1 | |
| SCHEMBL6511925 | 0.88 | HTT (0.51) | PKMMEN1KMT2AFFAR1RIPK1 | |
| SCHEMBL6512683 | 0.88 | MEP1B (0.46) | FFAR1HSP90AA1EGFRCSF1RMEP1B | |
| SCHEMBL6508483 | 0.85 | TSHR (0.45) | KMT2AFFAR1RIPK1SMN1; SMN2HSP90AA1 | |
| SCHEMBL6509513 | 0.85 | SLC6A9 (0.41) | PKMFOLH1MEN1KMT2AFFAR1 | |
| SCHEMBL6513388 | 0.85 | MEP1B (0.46) | MEN1KMT2AFFAR1MAPTMEP1B | |
| SCHEMBL6511878 | 0.85 | FFAR1 (0.49) | PKMFOLH1MEN1KMT2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |