Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.43 |
| ▸ | MTOR | P42345 | 3/20 | 0.43 |
| ▸ | PDE2A | O00408 | 2/20 | 0.42 |
| ▸ | BRAF | P15056 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL332978 | 0.82 | BRAF (0.60) | BRAF | |
| SCHEMBL30523428 | 0.81 | XDH (0.67) | XDHPIK3CAMTORPDE2ABRAF | |
| SCHEMBL20565 | 0.81 | XDH (0.67) | XDHPIK3CAMTORPDE2ABRAF | |
| SCHEMBL28878261 | 0.79 | XDH (0.47) | XDHPIK3CAMTORPDE2ABRAF | |
| SCHEMBL1808629 | 0.78 | ADORA3 (0.42) | XDHBRAFMAPTLMNAHTT | |
| SCHEMBL8885460 | 0.77 | XDH (0.45) | XDHPIK3CAMTORPDE2ABRAF | |
| SCHEMBL16146881 | 0.77 | ADORA3 (0.50) | XDHPIK3CAMTORPDE2AMAPT | |
| SCHEMBL5699092 | 0.76 | HTT (0.60) | MAPTLMNAHTT | |
| Hydrochloric Acid SCHEMBL7735734 | 0.75 | ADORA3 (0.49) | XDHPIK3CAMTORPDE2AMAPT | |
| SCHEMBL16145784 | 0.75 | ADORA3 (0.61) | LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043268-A1 | Inhibition of viruses | MEDICAL RESEARCH COUNCIL (GB) | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043268-A1 | Inhibition of viruses | RNASE1, HNRNPA1, RNASEH1 | XDH 1651/4885PIK3CA 2824/4885MTOR 4401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.