Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512010 | 0.84 | LTB4R (0.42) | HDAC3HDAC1HDAC2HDAC8MTNR1A | |
| SCHEMBL6511657 | 0.84 | HDAC3 (0.50) | HDAC3HDAC1HDAC2HDAC8MTNR1A | |
| SCHEMBL6512357 | 0.83 | TAS2R14 (0.43) | HDAC3HDAC1HDAC2HDAC8THRB | |
| SCHEMBL6511823 | 0.82 | LTB4R (0.40) | HDAC3HDAC1HDAC2HDAC8MTNR1A | |
| SCHEMBL6512519 | 0.82 | POLB (0.50) | HDAC3HDAC1HDAC2HDAC8THRB | |
| SCHEMBL6511947 | 0.81 | MTNR1A (0.47) | HDAC3HDAC1HDAC2HDAC8MTNR1A | |
| SCHEMBL6515044 | 0.80 | ALDH1A1 (0.41) | HDAC3HDAC1HDAC2HDAC8THRB | |
| SCHEMBL6510830 | 0.79 | POLB (0.45) | HDAC3HDAC1HDAC2HDAC8THRB | |
| SCHEMBL6513642 | 0.79 | ESR1 (0.49) | HDAC3HDAC1HDAC2HDAC8THRB | |
| SCHEMBL6531193 | 0.78 | LTA4H (0.46) | HDAC3HDAC1HDAC2HDAC8MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |