Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509195 | 0.84 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL332859 | 0.80 | LMNA (0.54) | LMNASMN1; SMN2ALDH1A1TSHRMAPT | |
| SCHEMBL12845801 | 0.78 | HPGD (0.51) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL9852571 | 0.78 | LMNA (0.51) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL8814469 | 0.77 | LMNA (0.50) | LMNASMN1; SMN2ALDH1A1TSHRMAPT | |
| SCHEMBL9414491 | 0.75 | LMNA (0.43) | LMNASMN1; SMN2ALDH1A1TSHRMAPT | |
| SCHEMBL21783784 | 0.74 | LMNA (0.47) | LMNASMN1; SMN2TSHRMAPT | |
| SCHEMBL6362210 | 0.73 | LMNA (0.41) | LMNAALDH1A1TSHRMAPTHPGD | |
| SCHEMBL8780022 | 0.73 | LMNA (0.41) | LMNAALDH1A1TSHRMAPTHPGD | |
| SCHEMBL9016334 | 0.73 | LMNA (0.53) | LMNASMN1; SMN2ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877630-B1 | CONTRAST MEDIA | AMERSHAM HEALTH AS (NO) | 2005-03-23 | — | — | EP | disclosed |
| US-6423296-B1 | COMPOSITE MAGNETIC PARTICLES FORMED IRON OXIDE PARTICLES WATER AND POLYSACCHARIDE, CLEVAGE OF POLYSACCHARIDE, FERROOUS SALTS, COOLING | AMERSHAM HEALTH AS (NO) | 2002-07-23 | — | — | US | disclosed |
| EP-0877630-A2 | CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997025073-A2 | CONTRAST MEDIA | NYCOMED IMAGING A/S (NO) | 1997-07-17 | — | — | WO | disclosed |