Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512372 | 0.84 | LMNA (0.42) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL9852571 | 0.82 | LMNA (0.51) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL11859680 | 0.80 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL12845801 | 0.79 | HPGD (0.51) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL332859 | 0.79 | LMNA (0.54) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL21783784 | 0.78 | LMNA (0.47) | LMNASMN1; SMN2TSHRMAPK1RAB9A | |
| SCHEMBL9016334 | 0.77 | LMNA (0.53) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL8230945 | 0.77 | LMNA (0.53) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL19756076 | 0.77 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL17211607 | 0.77 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877630-B1 | CONTRAST MEDIA | AMERSHAM HEALTH AS (NO) | 2005-03-23 | — | — | EP | disclosed |
| US-6423296-B1 | COMPOSITE MAGNETIC PARTICLES FORMED IRON OXIDE PARTICLES WATER AND POLYSACCHARIDE, CLEVAGE OF POLYSACCHARIDE, FERROOUS SALTS, COOLING | AMERSHAM HEALTH AS (NO) | 2002-07-23 | — | — | US | disclosed |