Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | TLR4 | O00206 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8210076 | 0.90 | G6PC1 (0.56) | NPC1RAB9ATDP1RELACHRM5 | |
| SCHEMBL3653593 | 0.89 | KDM4E (0.51) | NPC1RAB9ATDP1RELACHRM5 | |
| SCHEMBL2123173 | 0.84 | LTA4H (0.57) | NPC1RAB9ATDP1TP53ALDH1A1 | |
| SCHEMBL4949651 | 0.83 | RELA (0.54) | NPC1RAB9ATDP1RELATP53 | |
| SCHEMBL9451937 | 0.82 | MAOB (0.56) | NPC1RAB9ATDP1RELACHRM5 | |
| SCHEMBL9330295 | 0.82 | RELA (0.57) | NPC1RAB9ATDP1RELATP53 | |
| SCHEMBL1930129 | 0.81 | ALDH1A1 (0.61) | RELATP53ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL16619043 | 0.80 | CHRM5 (0.60) | NPC1RAB9ATDP1RELACHRM5 | |
| SCHEMBL27947937 | 0.79 | MAOB (0.53) | RELACHRM5MAOBCYP1A2G6PC1 | |
| SCHEMBL3836001 | 0.78 | TUBB4A (0.62) | NPC1TDP1TP53ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119667-B2 | Carbonates of fenicol antibiotics | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) | 2012-02-21 | — | — | US | claimed |
| WO-1997017950-A1 | SHOULDER PROSTHESIS | ELI LILLY AND COMPANY (US) | 1997-05-22 | — | — | WO | claimed |
| WO-1997017950-A1 | SHOULDER PROSTHESIS | ELI LILLY AND COMPANY (US) | 1997-05-22 | — | — | WO | disclosed |