SCHEMBL6513442

SCHEMBL6513442

CC(NCc1cccc(F)c1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.56
MAOA P21397 2/20 0.56
SCN9A Q15858 1/20 0.56
MEP1B Q16820 2/20 0.52
ANPEP P15144 1/20 0.49
SLC1A1 P43005 2/20 0.49
CD274 Q9NZQ7 1/20 0.48
FFAR1 O14842 1/20 0.48
SRC P12931 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6237660 1.00 MAOB (0.56) MAOBMAOASCN9AMEP1BANPEP
SCHEMBL8802555 0.86 MAOB (0.73) MAOBMAOASCN9A
SCHEMBL2933427 0.85 MAOB (0.81) MAOBMAOASCN9A
SCHEMBL2933423 0.85 MAOB (0.81) MAOBMAOASCN9A
SCHEMBL18475402 0.83 MEP1B (0.54) MEP1BCD274
SCHEMBL6240677 0.83 ALDH1A1 (0.54) MEP1BCD274
SCHEMBL29176912 0.82 MAOB (0.55) MAOBMAOASCN9AMEP1BANPEP
SCHEMBL1147679 0.82 MEP1B (0.50) MEP1BCD274
SCHEMBL3556483 0.81 SIGMAR1 (0.55) MEP1BCD274
SCHEMBL497818 0.81 SIGMAR1 (0.55) MEP1BCD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3303367-B1 STABILIZED MINIMAL COILED-COIL MIMETICS UNIV NEW YORK (US) 2025-06-18 EP disclosed
WO-2024130161-A2 NOVEL CAMPTOTHECIN DERIVATIVES AND CONJUGATES THEREOF BIONECURE THERAPEUTICS INC (US) 2024-06-20 WO disclosed
US-20240190930-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME UNIV NEW YORK (US) 2024-06-13 US disclosed
US-20240124539-A1 CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME NEW YORK UNIVERSITY 2024-04-18 US disclosed
US-11891422-B2 NEMO coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2024-02-06 US disclosed
US-20240034753-A1 THERAPEUTIC PEPTIDES COHBAR, INC. 2024-02-01 US disclosed
US-11753445-B2 Therapeutic peptides COHBAR, INC. (US) 2023-09-12 US disclosed
US-20230218710-A1 METHOD OF TREATING CORONAVIRUS INFECTIONS COHBAR, INC. 2023-07-13 US disclosed
US-20230137562-A1 TAU AGGREGATION INHIBITORS ADRX, INC. 2023-05-04 US disclosed
EP-4135738-A2 METHOD OF TREATING CORONAVIRUS INFECTIONS Cohbar Inc. (US) 2023-02-22 EP disclosed
US-20200062804-A1 PEPTIDE INHIBITORS OF TRANSCRIPTION FACTOR AGGREGATION ADRX, INC. 2020-02-27 US disclosed
EP-3519431-A1 THERAPEUTIC MOTS-C RELATED PEPTIDES Cohbar Inc. (US) 2019-08-07 EP disclosed
WO-2019036725-A2 TAU AGGREGATION PEPTIDE INHIBITORS ADRX, INC. (US) 2019-02-21 WO disclosed
WO-2018226992-A1 TAU AGGREGATION INHIBITORS ADRX, INC. (US) 2018-12-13 WO disclosed
WO-2018156892-A1 PEPTIDE INHIBITORS OF TRANSCRIPTION FACTOR AGGREGATION ADRX, INC. (US) 2018-08-30 WO disclosed
US-20180162907-A1 STABILIZED MINIMAL COILED-COIL MIMETICS NEW YORK UNIVERSITY 2018-06-14 US disclosed
EP-3303367-A1 STABILIZED MINIMAL COILED-COIL MIMETICS New York University (US) 2018-04-11 EP disclosed
WO-2018064098-A1 THERAPEUTIC MOTS-C RELATED PEPTIDES COHBAR, INC. (US) 2018-04-05 WO disclosed
WO-2016201007-A1 STABILIZED MINIMAL COILED-COIL MIMETICS NEW YORK UNIVERSITY (US) 2016-12-15 WO disclosed
WO-2005030735-A1 TRIAZINES DERIVATIVES AS CELL ADHESION INHIBITORS RANBAXY LABORATORIES LIMITED (IN) 2005-04-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240124539-A1 CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME SOS2, SOS1, F2 MAOB 2930/4885MAOA 4182/4885SCN9A 3787/4885
US-11891422-B2 NEMO coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH MAOB 2303/4885MAOA 3280/4885SCN9A 2323/4885
US-20180162907-A1 STABILIZED MINIMAL COILED-COIL MIMETICS COIL, CALCOCO2, CRYZ MAOB 4811/4885MAOA 4815/4885SCN9A 4092/4885
US-20240190930-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME COIL, CALCOCO2, NCAPH MAOB 2203/4885MAOA 3215/4885SCN9A 2241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.