Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.45 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242130 | 0.88 | KMT2A (0.52) | LMNAALDH1A1CDK2MAPTNPSR1 | |
| SCHEMBL25139634 | 0.85 | LMNA (0.45) | LMNAALDH1A1CDK2KMOMAPT | |
| SCHEMBL25139687 | 0.85 | LMNA (0.45) | LMNAALDH1A1CDK2KMOMAPT | |
| SCHEMBL23226415 | 0.85 | MCL1 (0.53) | CDK2KMOMCL1KMT2A | |
| SCHEMBL14564407 | 0.83 | MAPT (0.50) | LMNAALDH1A1CDK2KMOMAPT | |
| SCHEMBL28977346 | 0.82 | AKR1C3 (0.49) | LMNAALDH1A1KMOKEAP1NFE2L2 | |
| SCHEMBL30275134 | 0.82 | MEN1 (0.50) | ALDH1A1CDK2MAPTAKR1C3AKR1C2 | |
| SCHEMBL19871241 | 0.79 | ALDH1A1 (0.51) | LMNAALDH1A1CDK2KMOMAPT | |
| SCHEMBL21614277 | 0.78 | CDK2 (0.47) | LMNAALDH1A1CDK2KMOMAPT | |
| SCHEMBL341492 | 0.78 | GPR84 (0.62) | LMNAALDH1A1MAPTKMT2ACDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050203166-A1 | Indole-3-acetic acid derivatives | CANCER RESEARCH TECHNOLOGY LIMITED | 2005-09-15 | — | — | US | disclosed |
| US-6890948-B1 | Use of indole-3-acetic acid derivatives in medicine | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2005-05-10 | — | — | US | disclosed |
| EP-1296676-B1 | USE OF INDOLE-3-ACETIC ACID DERIVATIVES IN MEDICINE | CANCER REC TECH LTD (GB) | 2004-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203166-A1 | Indole-3-acetic acid derivatives | ADCY3, GPR3, HCAR3 | LMNA 4515/4885ALDH1A1 176/4885CDK2 3458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.