SCHEMBL28648779

SCHEMBL28648779

O=[P](c1ccc(Br)cc1)c1ccc(Br)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.50
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
ALDH1A1 P00352 4/20 0.38
MAPK1 P28482 3/20 0.38
ALOX15 P16050 2/20 0.38
CA2 P00918 6/20 0.36
CA1 P00915 5/20 0.36
TDP1 Q9NUW8 1/20 0.35
PLCG1 P19174 1/20 0.35
TSHR P16473 1/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
FAAH O00519 1/20 0.33
MGLL Q99685 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3757571 0.73 CYP2A6 (0.57) CYP2A6CES2CES1ALDH1A1MAPK1
SCHEMBL4276353 0.71 CYP2A6 (0.53) CYP2A6CES2CES1ALDH1A1MAPK1
SCHEMBL18508 0.71
SCHEMBL183976 0.69 ACHE (0.50) CYP2A6CES2CES1ALDH1A1CA2
SCHEMBL11916255 0.69 CYP2A6 (0.50) CYP2A6CES2CES1ALDH1A1MAPK1
SCHEMBL9717534 0.69 CYP2A6 (0.50) CYP2A6CES2CES1ALDH1A1MAPK1
SCHEMBL1304998 0.69 LMNA (0.50) CYP2A6CES2CES1ALDH1A1MAPK1
SCHEMBL2884210 0.69 CYP2A6 (0.50) CYP2A6CES2CES1ALDH1A1MAPK1
SCHEMBL11770595 0.69 CYP2A6 (0.50) CYP2A6CES2CES1ALDH1A1MAPK1
SCHEMBL65149 0.69 MEN1 (0.50) ALDH1A1MAPK1ALOX15CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114031639-B Preparation method of biphospide with P-O-C-P structure 烟台大学 2024-07-12 CN claimed
CN-119613454-A Preparation method of difluoromethyl-containing compound 昆明理工大学 2025-03-14 CN disclosed
CN-116041392-B Compound containing phosphate group, preparation method and application thereof 中国科学院长春应用化学研究所 2024-11-12 CN disclosed
CN-114031639-B Preparation method of biphospide with P-O-C-P structure 烟台大学 2024-07-12 CN disclosed
CN-114805430-B Preparation method of selenophosphide and thiophosphoride 烟台大学 2024-02-13 CN disclosed
CN-116715698-A Preparation method of 6-phosphoryl 1,2, 4-triazine-3, 5 (2H, 4H) -diketone derivative 河北工业大学 2023-09-08 CN disclosed
CN-113583042-B Preparation method of phosphoryl fluoride compound 烟台大学 2023-08-29 CN disclosed
CN-116462709-A Phosphate group-containing compound, preparation method thereof and application thereof in perovskite light-emitting device 中国科学院长春应用化学研究所 2023-07-21 CN disclosed
CN-116041392-A Compound containing phosphate group, preparation method and application thereof 中国科学院长春应用化学研究所 2023-05-02 CN disclosed
CN-114805430-A Preparation method of seleno-phosphide and thiophosphite 烟台大学 2022-07-29 CN disclosed
CN-114031639-A Preparation method of biphosphonate with P-O-C-P structure 烟台大学 2022-02-11 CN disclosed
CN-113583042-A Preparation method of phosphoryl fluoride compound 烟台大学 2021-11-02 CN disclosed