SCHEMBL6520330

SCHEMBL6520330

Cc1ccc(COc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 5/20 0.76
RXRB P28702 5/20 0.76
NPC1 O15118 1/20 0.76
POLB P06746 1/20 0.76
RAB9A P51151 1/20 0.76
SMN1; SMN2 Q16637 1/20 0.76
MAOB P27338 1/20 0.76
PARP10 Q53GL7 2/20 0.73
NR4A2 P43354 4/20 0.72
NR4A1 P22736 1/20 0.72
NR4A3 Q92570 1/20 0.72
ALDH1A1 P00352 1/20 0.69
MAPT P10636 1/20 0.69
MAPK1 P28482 1/20 0.69
PLA2G4B P0C869 2/20 0.66
SRD5A2 P31213 1/20 0.66
NR1H4 Q96RI1 1/20 0.64
PTPRC P08575 1/20 0.62
PTPN2 P17706 1/20 0.62
PTPN1 P18031 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16550312 1.00 RXRA (0.76) RXRARXRBNPC1POLBRAB9A
SCHEMBL1756453 0.95 RXRA (0.69) RXRARXRBNPC1POLBRAB9A
SCHEMBL8134318 0.91 NR4A2 (0.85) RXRARXRBNPC1POLBRAB9A
SCHEMBL28335896 0.86 RAB9A (1.00) RXRARXRBNPC1POLBRAB9A
SCHEMBL1186510 0.86 RAB9A (1.00) RXRARXRBNPC1POLBRAB9A
SCHEMBL25555307 0.86 RXRA (1.00) RXRARXRBNPC1POLBRAB9A
SCHEMBL8861229 0.86 RXRA (1.00) RXRARXRBNPC1POLBRAB9A
SCHEMBL1092229 0.86 MAOB (1.00) SMN1; SMN2MAOBPARP10ALDH1A1MAPT
SCHEMBL13383911 0.86 RXRA (0.57) RXRARXRBNPC1POLBRAB9A
SCHEMBL31556120 0.85 ALDH1A1 (0.78) NPC1POLBRAB9ASMN1; SMN2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4098816-A HYPOGLYCEMIC AGENTS AND ANTILIPEMIC AGENTS BEECHAM GROUP LIMITED (GB) 1978-07-04 US claimed
WO-2017083520-A1 ANIMAL THERAPEUTIC AND FEED COMPOSITIONS AND METHODS OF USE CADENA BIO, INC. (US) 2017-05-18 WO disclosed
WO-2016122887-A9 OLIGOSACCHARIDE COMPOSITIONS FOR USE ANIMAL FEED AND METHODS OF PRODUCING THEREOF MIDORI USA, INC. (US) 2017-02-02 WO disclosed
US-20160366909-A1 OLIGOSACCHARIDE COMPOSITIONS FOR USE AS ANIMAL FEED AND METHODS OF PRODUCING THEREOF MIDORI USA, INC. (US) 2016-12-22 US disclosed
WO-2016122940-A1 METHODS OF PRODUCING ANHYDROSUGAR ALCOHOLS MIDORI USA, INC. (US) 2016-08-04 WO disclosed
WO-2016122885-A1 OLIGOSACCHARIDE COMPOSITIONS FOR USE IN NUTRITIONAL COMPOSITIONS, AND METHODS OF PRODUCING THEREOF MIDORI USA, INC. (US) 2016-08-04 WO disclosed
WO-2016122884-A1 OLIGOSACCHARIDE COMPOSITIONS FOR USE AS FOOD INGREDIENTS AND METHODS OF PRODUCING THEREOF MIDORI USA, INC. (US) 2016-08-04 WO disclosed
WO-2016122887-A1 OLIGOSACCHARIDE COMPOSITIONS FOR USE ANIMAL FEED AND METHODS OF PRODUCING THEREOF MIDORI USA, INC. (US) 2016-08-04 WO disclosed
US-9238845-B2 Methods of producing sugars from biomass feedstocks MIDORI USA, INC. (US) 2016-01-19 US disclosed
WO-2016007778-A1 OLIGOSACCHARIDE COMPOSITIONS AND METHODS FOR PRODUCING THEREOF MIDORI USA, INC. (US) 2016-01-14 WO disclosed
WO-2013163230-A2 BIO-BASED POLYMERS AND METHODS OF PRODUCING THEREOF Midori Renewables, Inc. (US) 2013-10-31 WO disclosed
US-20110003851-A1 SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS THAT ACTIVATE HEMATOPOIETIC GROWTH FACTOR RECEPTORS LIGAND PHARMACEUTICALS, INC. (US) 2011-01-06 US disclosed
US-7494537-B2 Thermochromic coloring color-memory composition and thermochromic coloring color-memory microcapsule pigment containing the same THE PILOT INK CO., LTD. (JP) 2009-02-24 US disclosed
EP-0273418-B1 Heat-sensitive recording material using chromeno compound KANZAKI PAPER MFG CO LTD (JP) 1993-11-24 EP disclosed
EP-0482668-B1 HEAT SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1993-08-04 EP disclosed
US-5187143-A Thermographic mixture of basic leuco dye and color developer comprising a zinc salt of terephthaldehydic acid or a composite salt also containing an aromatic acid KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1993-02-16 US disclosed
EP-0482668-A1 Heat sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1992-04-29 EP disclosed
US-4803193-A COLORFASTNESS; READABLE BY OPTICAL CHARACTER-READING DEVICES KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1989-02-07 US disclosed
EP-0273418-A2 Heat-sensitive recording material using chromeno compound KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-07-06 EP disclosed
US-4098816-A HYPOGLYCEMIC AGENTS AND ANTILIPEMIC AGENTS BEECHAM GROUP LIMITED (GB) 1978-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160366909-A1 OLIGOSACCHARIDE COMPOSITIONS FOR USE AS ANIMAL FEED AND METHODS OF PRODUCING THEREOF FUT5, FUT6, OSTC RXRA 4450/4885RXRB 4476/4885NPC1 3433/4885
US-20110003851-A1 SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS THAT ACTIVATE HEMATOPOIETIC GROWTH FACTOR RECEPTORS MPL, CSF3R, CSF1R RXRA 650/4885RXRB 743/4885NPC1 4677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.