Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.52 |
| ▸ | NPC1 | O15118 | 8/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4349050 | 0.84 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2EPHX2TSHR | |
| SCHEMBL4347487 | 0.84 | EPHX1 (0.56) | RAB9ANPC1SMN1; SMN2EPHX2TSHR | |
| SCHEMBL4347065 | 0.81 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2EPHX2TSHR | |
| SCHEMBL6568610 | 0.79 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2EPHX2TSHR | |
| SCHEMBL4352945 | 0.75 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2EPHX2TSHR | |
| SCHEMBL4347284 | 0.75 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2EPHX2TSHR | |
| SCHEMBL4354309 | 0.75 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2EPHX2TSHR | |
| SCHEMBL6567606 | 0.74 | L3MBTL1 (0.53) | RAB9ANPC1SMN1; SMN2HTTLMNA | |
| SCHEMBL4357508 | 0.74 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2EPHX2TSHR | |
| SCHEMBL6521514 | 0.74 | ALDH1A1 (0.54) | RAB9ANPC1SMN1; SMN2EPHX2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065760-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES AND USE THEREOF | JERINI AG (DE) | 2011-03-17 | — | — | US | claimed |
| CN-1701061-A | Novel compounds for inhibiting rotamase enzymes and uses thereof | JERINI AG (DE) | 2005-11-23 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065760-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES AND USE THEREOF | NR1I3, NR1D1, NR1D2 | RAB9A 4228/4885NPC1 815/4885SMN1; SMN2 1791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.