Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 2/20 | 0.37 |
| ▸ | ALPG | P10696 | 2/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26523553 | 0.84 | FDPS (0.51) | FDPSKMT2AALDH1A1POLBKCNH2 | |
| SCHEMBL24430222 | 0.83 | FDPS (0.58) | FDPSKMT2AALDH1A1POLBKCNH2 | |
| SCHEMBL4235515 | 0.82 | FDPS (0.62) | FDPSKMT2AALDH1A1POLBTSHR | |
| SCHEMBL12384352 | 0.81 | FDPS (0.56) | FDPSKMT2AALDH1A1POLBKCNH2 | |
| SCHEMBL486434 | 0.78 | — | — | |
| SCHEMBL18010007 | 0.78 | FDPS (0.53) | FDPSKMT2AALDH1A1POLBKCNH2 | |
| SCHEMBL3836216 | 0.76 | KMT2A (0.52) | FDPSKMT2AALDH1A1POLBKCNH2 | |
| Iodide SCHEMBL4268734 | 0.76 | — | — | |
| Hydrogen Sulfide SCHEMBL28101812 | 0.76 | — | — | |
| Bromide SCHEMBL1237833 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321091-A1 | SUBSTITUTED PYRIDAZINONES FOR USE IN THE TREATMENT OF NEUROMUSCULAR DISEASES | EDGEWISE THERAPEUTICS, INC. | 2023-10-12 | — | — | US | disclosed |
| US-20210188814-A1 | PYRIDAZINONE COMPOUNDS AND USES THEREOF | CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED (GB) | 2021-06-24 | — | — | US | disclosed |
| EP-0718288-B1 | Liquid hydrophobic salts, their preparation and their use in electrochemistry | HYDRO QUEBEC (CA) | 2005-06-29 | — | — | EP | disclosed |
| US-5683832-A | PHOTOVOLTAIC CELLS | ASULAB S.A. (CH) | 1997-11-04 | — | — | US | disclosed |
| EP-0718288-A1 | Liquid hydrophobic salts, their preparation and their use in electrochemistry | ASULAB S.A. (CH) | 1996-06-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188814-A1 | PYRIDAZINONE COMPOUNDS AND USES THEREOF | IL6, IL1B, IL1A | FDPS 912/4885KMT2A 4169/4885ALDH1A1 270/4885 |
| US-20230321091-A1 | SUBSTITUTED PYRIDAZINONES FOR USE IN THE TREATMENT OF NEUROMUSCULAR DISEASES | IL6, MUSK, SMN1; SMN2 | FDPS 842/4885KMT2A 3767/4885ALDH1A1 308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.