SCHEMBL652160

SCHEMBL652160

CCOC(=O)C1CCCCN1C

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 3/20 0.55
ALDH1A1 P00352 8/20 0.48
KDM4E B2RXH2 6/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
TSHR P16473 2/20 0.46
MAPK1 P28482 1/20 0.46
RECQL P46063 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.44
POLB P06746 2/20 0.44
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24846753 1.00 FKBP1A (0.55) FKBP1AALDH1A1KDM4EMEN1KMT2A
SCHEMBL13601738 0.95 FKBP1A (0.49) FKBP1AALDH1A1KDM4EMEN1KMT2A
SCHEMBL11490823 0.95 FKBP1A (0.49) FKBP1AALDH1A1KDM4EMEN1KMT2A
SCHEMBL11490824 0.95 FKBP1A (0.49) FKBP1AALDH1A1KDM4EMEN1KMT2A
SCHEMBL26039280 0.86 FKBP1A (0.43) FKBP1AALDH1A1KDM4EMEN1KMT2A
SCHEMBL9246148 0.81 CHRNB2 (0.50)
SCHEMBL24131501 0.81 RAB9A (0.50) FKBP1AALDH1A1TSHR
SCHEMBL9246142 0.81 FKBP1A (0.42) FKBP1AMEN1KMT2A
SCHEMBL19576693 0.81 FKBP1A (0.51) FKBP1AALDH1A1KDM4EMEN1KMT2A
SCHEMBL6782112 0.81 KDM4E (0.56) FKBP1AALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023189433-A1 ULTRAVIOLET RADIATION-CURABLE POLYSILOXANE COMPOSITION, AND DAMPING MATERIAL 株式会社タイカ 2023-10-05 WO disclosed
US-20230192620-A1 ANILINE COMPOUND USED AS RORy REGULATOR SHANGHAI LITEDD CO., LTD. (CN) 2023-06-22 US disclosed
WO-2021072140-A1 PRODRUGS OF MYELOPEROXIDASE INHIBITORS BIOHAVEN THERAPEUTICS LTD. (US) 2021-04-15 WO disclosed
CN-109912570-A A kind of preparation method of argatroban intermediate amidate 天津药物研究院药业有限责任公司 2019-06-21 CN disclosed
US-9709907-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-07-18 US disclosed
US-9709907-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-07-18 US disclosed
US-9500966-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-11-22 US disclosed
US-9500966-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-11-22 US disclosed
US-9340505-B2 Type III secretion inhibitors, analogs and uses thereof UNIVERSITY OF MASSACHUSETTS (US) 2016-05-17 US disclosed
US-20150362848-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-12-17 US disclosed
US-20030153505-A1 Dolastatin 15 derivatives BASF AKTIENGESELLSCHAFT (DE) 2003-08-14 US disclosed
US-6458765-B1 POLYPEPTIDES AS ANTICANCER AGENTS AND AGAINST CELL PROLIFERATION BASF AKTIENGESELLSCHAFT (DE) 2002-10-01 US disclosed
US-20010034419-A1 Radiation transparent molding materials MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2001-10-25 US disclosed
US-6143721-A FOR TREATING CANCER IN MAMMALS BASF AKTIENGESELLSCHAFT (DE) 2000-11-07 US disclosed
EP-0991658-A1 DOLASTATIN 15 DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 2000-04-12 EP disclosed
WO-1999003879-A1 DOLASTATIN 15 DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1999-01-28 WO disclosed
EP-0527427-B1 Catalysts and casting article, method, and composition MINNESOTA MINING & MFG (US) 1995-11-15 EP disclosed
US-5225513-A Orthopedic casting MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-07-06 US disclosed
EP-0527427-A2 Catalysts and casting article, method, and composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-02-17 EP disclosed
US-4190579-A Synthesis of beta-lactams from azetidine carboxylic acid esters RESEARCH CORPORATION (US) 1980-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192620-A1 ANILINE COMPOUND USED AS RORy REGULATOR RORB, RORA, RORC FKBP1A 155/4885ALDH1A1 536/4885KDM4E 1923/4885
US-20030153505-A1 Dolastatin 15 derivatives DBI, DDOST, BDKRB1 FKBP1A 2559/4885ALDH1A1 1840/4885KDM4E 2445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.