Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | OGA | O60502 | 2/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.33 |
| ▸ | GPR18 | Q14330 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6522876 | 0.84 | HPGD (0.40) | HPGDOGACYP4F2CYP4A11GPR55 | |
| SCHEMBL1036396 | 0.82 | CYP3A4 (0.45) | HPGDOGAGAAHTR2AKMT2A | |
| SCHEMBL1075972 | 0.76 | CYP3A4 (0.42) | HPGDOGAGAAHTR2AKMT2A | |
| SCHEMBL1037459 | 0.73 | CYP3A4 (0.41) | HPGDOGAGAAHTR2AALDH1A1 | |
| SCHEMBL1082548 | 0.72 | FAAH (0.56) | HPGDOGAGAAHTR2A | |
| SCHEMBL6525248 | 0.72 | HPGD (0.38) | HPGDOGAALDH1A1MAPTMAPK1 | |
| SCHEMBL6518965 | 0.72 | GPR18 (0.34) | OGAGPR55GPR18 | |
| SCHEMBL6521424 | 0.67 | GPR55 (0.37) | OGAGPR55GPR18 | |
| SCHEMBL6521897 | 0.66 | F10 (0.37) | OGAGPR55HTR1APPARG | |
| SCHEMBL1038304 | 0.66 | CYP3A4 (0.49) | OGAGAAHTR2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110053982-A1 | ETHER BENZYLIDENE PIPERIDINE 5-MEMBERED ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS | PFIZER INC. (US) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053982-A1 | ETHER BENZYLIDENE PIPERIDINE 5-MEMBERED ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS | FAAH, FAAH2, CNR2 | HPGD 382/4885OGA 1857/4885CYP4F2 609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.