Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 8/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 8/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 7/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 7/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632170 | 0.88 | MTNR1A (0.34) | PTGER4PTGER3PTGER1PTGER2 | |
| SCHEMBL11167641 | 0.77 | ALDH1A1 (0.46) | — | |
| SCHEMBL71453 | 0.69 | PTGER4 (0.68) | PTGER4PTGER3PTGER1PTGER2KEAP1 | |
| SCHEMBL563542 | 0.69 | KDM4E (0.35) | — | |
| SCHEMBL8875574 | 0.68 | PTGER1 (0.54) | PTGER4PTGER3PTGER1PTGER2KEAP1 | |
| SCHEMBL5154125 | 0.68 | PTGER1 (0.54) | PTGER4PTGER3PTGER1PTGER2KEAP1 | |
| SCHEMBL59198 | 0.67 | KEAP1 (0.65) | PTGER4PTGER3PTGER1PTGER2KEAP1 | |
| SCHEMBL6053663 | 0.67 | PTGER4 (0.81) | PTGER4PTGER3PTGER1PTGER2KEAP1 | |
| SCHEMBL28348523 | 0.65 | PTGER4 (0.50) | PTGER4PTGER3PTGER1PTGER2KEAP1 | |
| SCHEMBL31212507 | 0.65 | PTGER4 (0.77) | PTGER4PTGER3PTGER1PTGER2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2045483-A | — | — | None | — | — | JP | disclosed |
| JP-2005247778-A | METHOD FOR PRODUCING DIBENZOTHIEPINPROPIONIC ACID DERIVATIVE | MAEKAWA SHIGEJI | 2005-09-15 | — | — | JP | disclosed |
| JP-H0245483-A | PREPARATION OF OPTICALLY ACTIVE DIBENZOTHIEPINPROPIONIC ACID | NIPPON CHEMIPHAR CO LTD | 1990-02-15 | — | — | JP | disclosed |