Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | MC3R | P41968 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16972827 | 0.83 | TERT (0.41) | TERTALDH1A1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL6530748 | 0.77 | CYP11B2 (0.34) | GABRG2GABRB3GABRA5CYP11B1CYP11B2 | |
| SCHEMBL29209037 | 0.77 | PDE3B (0.35) | TERTGABRG2GABRB3GABRA5POLB | |
| SCHEMBL5004920 | 0.77 | KMT2A (0.40) | ALDH1A1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL30336272 | 0.77 | PDE3B (0.35) | TERTGABRG2GABRB3GABRA5POLB | |
| SCHEMBL3826803 | 0.76 | ALDH1A1 (0.36) | ALDH1A1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL3044452 | 0.74 | ALDH1A1 (0.40) | ALDH1A1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL27434591 | 0.74 | L3MBTL1 (0.36) | ALDH1A1KMT2AGABRG2GABRB3GABRA5 | |
| SCHEMBL3042096 | 0.74 | TERT (0.51) | TERTALDH1A1GABRA1GABRG2GABRB3 | |
| SCHEMBL18227101 | 0.72 | TERT (0.44) | TERTALDH1A1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082897-A1 | OXAZOLIDINONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-09-09 | — | — | WO | disclosed |