Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.39 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6526664 | 0.86 | GLS (0.49) | NPFFR1NPFFR2CYP2D6OPRK1GLS | |
| SCHEMBL825511 | 0.75 | KCNA5 (0.53) | KCNA5GLSNAMPTKDM4A | |
| SCHEMBL29430481 | 0.75 | KCNA5 (0.53) | KCNA5GLSNAMPTKDM4A | |
| SCHEMBL30159605 | 0.74 | KCNA5 (0.56) | KCNA5L3MBTL1NAMPTKDM4A | |
| SCHEMBL8018113 | 0.74 | KCNA5 (0.56) | KCNA5L3MBTL1NAMPTKDM4A | |
| SCHEMBL2066840 | 0.74 | SIGMAR1 (0.46) | NPFFR1NPFFR2CYP2D6KCNA3L3MBTL1 | |
| SCHEMBL5842937 | 0.73 | OPRK1 (0.75) | CYP2D6OPRM1OPRD1OPRK1 | |
| SCHEMBL11346624 | 0.72 | KCNA5 (0.51) | KCNA5GLSNAMPTKDM4A | |
| SCHEMBL7258326 | 0.72 | KCNA5 (0.53) | KCNA5GLSNAMPTKDM4A | |
| SCHEMBL11520059 | 0.71 | KCNA5 (0.52) | KCNA5GLSNAMPTKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005004796-A2 | SULFONYLAMINO PHENYLACETAMIDE DERIVATIVES AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2005-01-20 | — | — | WO | disclosed |